Antonyms of adj brainless

1 sense of brainless

Sense 1
brainless, headless -- (not using intelligence)

INDIRECT (VIA unintelligent) -> intelligent -- (having the capacity for thought and reason especially to a high degree; "is there intelligent life in the universe?"; "an intelligent question")

Similarity of adj brainless

1 sense of brainless

Sense 1
brainless, headless -- (not using intelligence)
       => unintelligent (vs. intelligent), stupid -- (lacking intelligence; "a dull job with lazy and unintelligent co-workers")

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