Antonyms of adj fatuous

1 sense of fatuous

Sense 1
asinine, fatuous, inane, mindless, vacuous -- (devoid of intelligence)

INDIRECT (VIA foolish) -> wise -- (having or prompted by wisdom or discernment; "a wise leader"; "a wise and perceptive comment")

Similarity of adj fatuous

1 sense of fatuous

Sense 1
asinine, fatuous, inane, mindless, vacuous -- (devoid of intelligence)
       => foolish (vs. wise) -- (devoid of good sense or judgment; "foolish remarks"; "a foolish decision")