Antonyms of adj one-horse

1 sense of one-horse

Sense 1
jerkwater, one-horse, pokey, poky -- (small and remote and insignificant; "a jerkwater college"; "passed a series of poky little one-horse towns")

INDIRECT (VIA provincial) -> cosmopolitan -- (composed of people from or at home in many parts of the world; especially not provincial in attitudes or interests; "his cosmopolitan benevolence impartially extended to all races and to all creeds"- T.B. Macaulay; "the ancient and cosmopolitan societies of Syria and Egypt"; "that queer, cosmopolitan, rather sinister crowd found around the Marseilles docks")

Similarity of adj one-horse

1 sense of one-horse

Sense 1
jerkwater, one-horse, pokey, poky -- (small and remote and insignificant; "a jerkwater college"; "passed a series of poky little one-horse towns")
       => provincial (vs. cosmopolitan) -- (characteristic of the provinces or their people; "deeply provincial and conformist"; "in that well-educated company I felt uncomfortably provincial"; "narrow provincial attitudes")