Antonyms of adj systemic
1 sense of systemic                                                     
Sense 1
systemic -- (affecting an entire system; "a systemic poison")
INDIRECT (VIA general) -> local -- (affecting only a restricted part or area of the body; "local anesthesia")
Similarity of adj systemic
1 sense of systemic                                                     
Sense 1
systemic -- (affecting an entire system; "a systemic poison")
       => general (vs. local) -- (affecting the entire body; "a general anesthetic"; "general symptoms")

