Synonyms/Hypernyms (Ordered by Estimated Frequency) of noun vicissitude

2 senses of vicissitude

Sense 1
vicissitude -- (a variation in circumstances or fortune at different times in your life or in the development of something; "the project was subject to the usual vicissitudes of exploratory research")
       => variation, fluctuation -- (an instance of change; the rate or magnitude of change)

Sense 2
vicissitude -- (mutability in life or nature (especially successive alternation from one condition to another))
       => mutability, mutableness -- (the quality of being capable of mutation)