Antonyms of adj self-destructive

1 sense of self-destructive

Sense 1
self-destructive, suicidal -- (dangerous to yourself or your interests; "suicidal impulses"; "a suicidal corporate takeover strategy"; "a kamikaze pilot")

INDIRECT (VIA dangerous) -> safe -- (free from danger or the risk of harm; "a safe trip"; "you will be safe here"; "a safe place"; "a safe bet")

Similarity of adj self-destructive

1 sense of self-destructive

Sense 1
self-destructive, suicidal -- (dangerous to yourself or your interests; "suicidal impulses"; "a suicidal corporate takeover strategy"; "a kamikaze pilot")
       => dangerous (vs. safe), unsafe -- (involving or causing danger or risk; liable to hurt or harm; "a dangerous criminal"; "a dangerous bridge"; "unemployment reached dangerous proportions")

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